Background and‌ Purpose: Laterality is a controversial issue that related to lateralization or assignment of brain hemispheres to specific activities. The purpose of this study was to comparison of the self-concept, anxiety, and dexterity between left-handed and right-handed students. 
Method: The present study is causal-comparative. The population of the study consisted of all girls and boys students aged 9-14 years old in Tabriz city in 1395. After identifying selected schools, 30 left-handed right-handed and 30 right-handed students were selected through purposeful sampling. The research data obtained by using the handedness quetionnair (Chapman & Chapman, 1987), Piers-Harris children's self-concept scale (1981), Beck anxiety scale (1988) and Purdue Pegboard (Tiffin & Asher, 1948). For data analysis, independent t-test and multivariate analysis of variance were used.
Results: The results showed a significant difference between the self-concept and anxiety components between the two groups of the left-handed and right-handed students, but there was no significant difference between the two groups in terms of dexterity (P <0.05)
Conclusion: Based on the results of this study, it can be concluded that there is a difference between the left-handed and right-handed students in emotional, behavioral and motor dimensions, which should be considered by families and child psychologists.