Background and Purpose: The study aimed to investigate the effect of music therapy on symptoms, communication deficit, and social interaction of children with autism spectrum disorder.

Method: The present research was quasi-experimental with pretest- posttest control group. The statistical population consisted of all children with autism spectrum disorders in Tabriz that 50 of them (25 children in each group) were selected by convenience sampling method and assigned in experimental and control group randomly. Gilliam Autism Rating Scale (GARS) was used to gather of data. Analysis of the data was performed using analysis of covariance.

Results: The findings of this study showed that music therapy can increase communication and language skills and reduce symptoms of autism (P<0.05).

Conclusion: Based on the results of this study, inactive music therapy can be used as a rehabilitation method for children with autism. Implications of the results are discussed in the article.